It’s estimated that the human body contains anywhere from 250 to 350 different joints. A joint is where two bones meet and are held together with cartilage, tendons, ligaments, and/or nerves.[1] Without joints, you would not be able to sit, stand, or move! That’s why it’s so important to give your joints the natural support they need beginning with glucosamine and chondroitin.
Research shows that the combination of glucosamine and chondroitin can help support joint health by supporting healthy collagen and providing support for lubrication that may help the joints glide easily.[2]
Research is also showing that there is another natural ingredient—methylsulfonylmethane (MSM)—that can provide additional support when combined with glucosamine and chondroitin. This is the joint health trifecta!
What is MSM and What is it Used For?
MSM is a naturally occurring sulfur compound and sulfur is necessary for normal cartilage function.[3] Cartilage is vital to joint health because it is the flexible connective tissue that cushions the joints where the bones meet acting like a shock absorber that also lubricates the joints.[4]
According to a 2023 randomized, double-blind, placebo-controlled trial, which is considered the gold standard of research, an MSM supplement was shown to specifically support the knee joint.[5]
Research also shows that MSM may help support joints and muscles after exercise. A 2017 study featured half-marathoners and a 2013 study featured moderately active men and both studies found that the MSM supplement supported joint and muscle health.[6][7]
Triple Joint Support
Staying active and moving with comfort and ease is a key goal for most people. The advanced joint combination of glucosamine, chondroitin, and MSM work together to help support normal joint comfort. This combination includes 1500 mg of glucosamine, 1200 mg of chondroitin, and 1500 mg of MSM per three-tablet serving. Sometimes these three ingredients are combined with vitamin C for added connective tissue and antioxidant support. Make movement more comfortable with the combination of glucosamine, chondroitin, and MSM.
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References
1. Cleveland Clinic. Joints. 2023;July 18. https://my.clevelandclinic.org/health/body/25137-joints
2. Zhu X, Sang L, Wu D, Rong J, Jiang L. Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials. J Orthop Surg Res. 2018;13(1):170. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035477/?report=reader
3. Butawan M, Benjamin RL, Bloomer RJ. Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients. 2017;9(3):290. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372953/?report=reader
4. Cleveland Clinic. Cartilage. 2022;May 24. https://my.clevelandclinic.org/health/body/23173-cartilage
5. Toguchi A, Noguchi N, Kanno T, Yamada A. Methylsulfonylmethane improves knee quality of life in participants with mild knee pain: a randomized, double-blind, placebo-controlled trial. Nutrients. 2023;15(13). https://www.mdpi.com/2072-6643/15/13/2995
6. Withee ED, Tippens KM, Dehen R, et al. Effects of methylsulfonylmethane (MSM) on exercise-induced oxidative stress, muscle damage, and pain following a half-marathon: a double-blind, randomized, placebo-controlled trial. Journal of the International Society of Sports Nutrition. 2017;14. https://jissn.biomedcentral.com/articles/10.1186/s12970-017-0181-z
7. Kalman D, Fedman S, Samson A, Krieger D. A randomized double blind placebo controlled evaluation of MSM for exercise induced discomfort/pain. FASEB Journal. 2013;27(S1). https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.27.1_supplement.1076.7
8. Colletti A, Cicero A. Nutraceutical approach to chronic osteoarthritis: from molecular research to clinical evidence. Int J Mol Sci. 2021;22(23). https://www.mdpi.com/1422-0067/22/23/12920
9. Ripani U, Manzarbeitia-Arroba P, Guijarro-Leo S, Urrutia-Graña J, De Masi-De Luca A. Vitamin C May Help to Reduce the Knee's Arthritic Symptoms. Outcomes Assessment of Nutriceutical Therapy. Med Arch. 2019;73(3):173-177. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643354/?report=reader
